Center for Male Reproductive Medicine & Microsurgery

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Selected Publication & Abstract

Dr. Schlegel: Testicular sperm extraction for treatment of non-obstructive azoospermia in men with history of cryptorchidism.

Cryptorchidism is the most common genitourinary abnormality in male infants, affecting up to 6% of newborn infants. A significant concern in cryptorchidism is the potential impact on fertility, as non-scrotal testes are at a higher temperature than is ideal for normal spermatogenesis, which may result in germ cell loss. Even when corrected at an early age, cryptorchidism can result in non-obstructive azoospermia (NOA). Microdissection testicular sperm extraction (TESE) with intracytoplasmic... Read More

Dr. Goldstein: First report from the Andrology Research Consortium

First report from the Andrology Research Consortium

Dr. Schlegel: Severe testicular atrophy does not affect the success of microdissection testicular sperm extraction.

Bryson CF, Ramasamy R, Sheehan M, Palermo GD, Rosenwaks Z, Schlegel PN. Severe testicular atrophy does not affect the success of microdissection testicular sperm extraction. J Urol 191(1): 175-178, 2014.AbstractPURPOSE: Men with azoospermia and severe testicular atrophy may be counseled to avoid sperm retrieval due to perceived limited success. We evaluated the outcomes of microdissection testicular sperm extraction in men with severe testicular atrophy (volume 2 ml or less).MATERIALS AND... Read More

Dr. Schlegel: Age does not adversely affect sperm retrieval in men undergoing microdissection testicular sperm extraction.

Ramasamy R, Trivedi NN, Reifsnyder JE, Palermo GD, Rosenwaks Z, Schlegel PN.  Age does not adversely affect sperm retrieval in men undergoing microdissection testicular sperm extraction. Fertil Steril 101(3): 653-655, 2014.AbstractOBJECTIVE: To evaluate the effect of male age on the outcome of microdissection testicular sperm extraction (micro-TESE) and assisted reproductive technology.DESIGN: Clinical retrospective study.SETTING: Center for reproductive medicine at a tertiary university... Read More

Dr. Schlegel: Intracytoplasmic sperm injection (ICSI) in extreme cases of male infertility.

Palermo GD, Neri QV, Schlegel PN, Rosenwaks Z.  Intracytoplasmic sperm injection (ICSI) in extreme cases of male infertility. PLoS One, 9(12): ePub, 2014 (PubMed: 25437298).AbstractINTRODUCTION: Severely compromised spermatogenesis typical of men with virtual azoospermia or non-obstructive azoospermia requires an extreme search for spermatozoa. Our goal was to evaluate the usefulness of a meticulous search carried out in ejaculated or surgically retrieved specimens in achieving pre- and post-... Read More

Center for Male Reproductive Medicine & Microsurgery Weill Cornell Medicine
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New York, NY 10065