Selected Publication & Abstract

Expert Comment: Pregnancy After Chemotherapy in Male and Female Survivors of Childhood Cancer

The Lancet OncologyTAKE-HOME MESSAGEThis study evaluated the effects of chemotherapy on pregnancy in male and female survivors of childhood cancer not exposed to pelvic or cranial radiotherapy. This study gathered data from a subset of the Childhood Cancer Survivor Study cohort which followed 5-year survivors of the most common types of childhood cancer treated at 27 institutions in the USA and Canada between 1970 and 1999. The data set included 10 ,938 survivors and 3949 siblings of survivors... Read More

Dr. Schlegel: Vasectomy and Risk of Prostate Cancer

In a contemporary cohort, the association of vasectomy and prostate cancer is limited to low risk disease, and is likely related to increased detection of prostate cancer based on patterns of care rather than a biological effect of vasectomy on prostate cancer development.

Dr. Schlegel: Testicular sperm extraction for treatment of non-obstructive azoospermia in men with history of cryptorchidism.

Cryptorchidism is the most common genitourinary abnormality in male infants, affecting up to 6% of newborn infants. A significant concern in cryptorchidism is the potential impact on fertility, as non-scrotal testes are at a higher temperature than is ideal for normal spermatogenesis, which may result in germ cell loss. Even when corrected at an early age, cryptorchidism can result in non-obstructive azoospermia (NOA). Microdissection testicular sperm extraction (TESE) with intracytoplasmic... Read More

Dr. Goldstein: First report from the Andrology Research Consortium

First report from the Andrology Research Consortium

Dr. Schlegel: Severe testicular atrophy does not affect the success of microdissection testicular sperm extraction.

Bryson CF, Ramasamy R, Sheehan M, Palermo GD, Rosenwaks Z, Schlegel PN. Severe testicular atrophy does not affect the success of microdissection testicular sperm extraction. J Urol 191(1): 175-178, 2014.AbstractPURPOSE: Men with azoospermia and severe testicular atrophy may be counseled to avoid sperm retrieval due to perceived limited success. We evaluated the outcomes of microdissection testicular sperm extraction in men with severe testicular atrophy (volume 2 ml or less).MATERIALS AND... Read More

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